What causes vitiligo?
Vitiligo is caused by the lack of a pigment called melanin in the skin. Melanin is produced by skin cells called melanocytes, and it gives your skin its colour.
In vitiligo, there are not enough working melanocytes to produce enough melanin in your skin. This causes white patches to develop on your skin or hair. It’s not clear exactly why the melanocytes disappear from the affected areas of skin.
- Autoimmune disorder: The affected person’s immune system may develop antibodies that destroy melanocytes.
- Genetic factors: Certain factors that may increase the chance of getting vitiligo can be inherited. About 30% of vitiligo cases run in families.
- Neurogenic factors: A substance that is toxic to melanocytes may be released at nerve endings in the skin.
- Self-destruction: A defect in the melanocytes causes them to destroy themselves.
Vitiligo may also be triggered by certain events, such as physical or emotional stress. Because none of the explanations seem to completely account for the condition, it’s possible that a combination of these factors is responsible for vitiligo.
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